I've just been following an autistic savant on TikTok who's come up with her own theories on many of these comorbidities and the biochemical pathways they have in common. Lots of it (to my understanding) lines up with the RCCX theory (though much of it is over my head).
My autistic daughter has just had genetic testing and all these things are falling into place.
You can see some of Kimberly's videos where she explains her theories here:
"This journey began with my realization of the striking commonality in comorbidity clusters among autistic individuals, prompting me to investigate the underlying systemic issues following my daughter’s nonverbal autism diagnosis. It became evident that such identical comorbidities couldn’t exist without a common denominator as a root cause, which led me to delve deeper into the BH4 pathway. Here, I blend practical teaching strategies with an in-depth exploration of the genetic and biochemical foundations of neurodivergence. "
The problem she has is that she's done this on her own, not through a university, so getting any university researchers to pay any attention seems to be difficult.
You're welcome. Thank you for sharing Kimberly information and commenting. I agree, it looks like she's talking about the same issues. Hopefully someone has pointed her to RCCX website.
You might be interested in the RCCX Facebook group (called RCCX and Chronic Illness Discussion Group) that Dr. Meglathery runs. One other resource you might find helpful - I did a RCCX related follow-up newsletter more focused on 21 hydroxylase and the RCCX - CAPs profile. If you try and can't fully open it, let me know and I can share it with you. https://courtneysnydermd.substack.com/p/how-mutations-on-one-gene-may-predispose?r=2rxjs4 Thank you again for commenting.
Hi Dr Snyder, thanks so much for this post.
I've just been following an autistic savant on TikTok who's come up with her own theories on many of these comorbidities and the biochemical pathways they have in common. Lots of it (to my understanding) lines up with the RCCX theory (though much of it is over my head).
My autistic daughter has just had genetic testing and all these things are falling into place.
You can see some of Kimberly's videos where she explains her theories here:
https://www.tiktok.com/@kimberlykitzerow
From her website:
"This journey began with my realization of the striking commonality in comorbidity clusters among autistic individuals, prompting me to investigate the underlying systemic issues following my daughter’s nonverbal autism diagnosis. It became evident that such identical comorbidities couldn’t exist without a common denominator as a root cause, which led me to delve deeper into the BH4 pathway. Here, I blend practical teaching strategies with an in-depth exploration of the genetic and biochemical foundations of neurodivergence. "
https://kimberlyseducationalresources.org/
The problem she has is that she's done this on her own, not through a university, so getting any university researchers to pay any attention seems to be difficult.
I do think she's onto something.
You're welcome. Thank you for sharing Kimberly information and commenting. I agree, it looks like she's talking about the same issues. Hopefully someone has pointed her to RCCX website.
You might be interested in the RCCX Facebook group (called RCCX and Chronic Illness Discussion Group) that Dr. Meglathery runs. One other resource you might find helpful - I did a RCCX related follow-up newsletter more focused on 21 hydroxylase and the RCCX - CAPs profile. If you try and can't fully open it, let me know and I can share it with you. https://courtneysnydermd.substack.com/p/how-mutations-on-one-gene-may-predispose?r=2rxjs4 Thank you again for commenting.